Kiyotoshi Satoh
佐藤 清敏 サトウ キヨトシ

政策・メディア研究科特任講師
学位博士(医学)
専門分野腫瘍生物学
担当科目プロテオーム解析実習 (TTCK),プロテオーム解析実習 (TTCK)
主要著作・論文・作品Matsumine A., Ogai A., Senda T., Okumura N., Satoh K., Baeg G. H., Kawahara T., Kobayashi S., Okada M., Toyoshima K., Akiyama T. Binding of APC to the human homolog of the Drosophila discs large tumor suppressor protein.
Science 272(5264):1020-1023 (1996).

Satoh K., Yanai H., Senda T., Kohu K., Nakamura T., Okumura N., Matsumine A., Kobayashi S., Toyoshima K., Akiyama T. DAP-1, a novel protein that interacts with the guanylate kinase-like domains of hDLG and PSD-95.
Genes to Cells 2(6):415-424 (1997).

Satoh K., Morishita T., Haraguchi K., Kakinuma N., Akiyama T., Senda T.
Expression and localization of the LGN protein in the mouse brain with reference to its relationship with G alpha i2.
Medical Electron Microscopy 32(4):221-225 (1999).

Yanai H., Satoh K., Matsumine A., Akiyama T. The colorectal tumour suppressor APC is present in the NMDA-receptor-PSD-95 complex in the brain.
Genes to Cells 5(10):815-822 (2000).

Haraguchi K., Satoh K., Yanai H., Hamada F., Kawabuchi M., Akiyama T.
The hDLG-associated protein DAP interacts with dynein light chain and neuronal nitric oxide synthase.
Genes to Cells 5(11):905-911 (2000).

Kim M., Ogawa H., Kohu K., Ichikawa M., Satoh K., Ishidao T., Nada S., Akiyama T. Binding of the mammalian homolog of the Drosophila discs large tumor suppressor protein to the ribosome receptor.
Biochem. Biophys. Res. Commun. 294(5):1151-1154 (2002).

Satoh K., Kasai M., Ishidao T., Tago K., Ohwada S., Hasegawa Y., Senda T., Takada S., Nada S., Nakamura T., Akiyama T. Anteriorization of neural fate by inhibitor of beta-catenin and T cell factor (ICAT), a negative regulator of Wnt signaling.
Proc. Natl. Acad. Sci. USA 101(21):8017-8021 (2004).

Kasai M., Satoh K., Akiyama T. Wnt signaling regulates the sequential onset of neurogenesis and gliogenesis via induction of BMPs.
Genes to Cells 10(8):777-783 (2005).

Yamada M., Ohnishi J., Ohkawara B., Iemura S., Satoh K., Hyodo-Miura J., Kawachi K., Natsume T., Shibuya H. NARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF).
The Journal of Biological Chemistry 281(30):20749-20760 (2006).

Hasegawa Y., Satoh K., Iizuka-Kogo A., Shimomura A., Nomura R., Akiyama T., Senda T. Loss of ICAT gene function leads to arrest of ureteric bud branching and renal agenesis.
Biochem. Biophys. Res. Commun. 362(4):988-994 (2007).

Satoh K., Ohnishi J., Sato A., Takeyama M., Iemura S., Natsume T., Shibuya H. Nemo-Like Kinase-Myocyte Enhancer Factor 2A signaling regulates anterior formation in Xenopus development.
Molecular and Cellular Biology 27(21):7623-7630 (2007).

Watanabe Y., Itoh S., Goto T., Ohnishi E., Inamitsu M., Itoh F., Satoh K., Wiercinska E., Yang W., Shi L., Tanaka A., Nakano N., Mommaas A. M., Shibuya H., Ten Dijke P., Kato M. TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling.
Molecular Cell 37(1):123-134 (2010).

Takemura Y., Satoh M., Satoh K., Hamada H., Sekido Y., Kubota S. High dose of ascorbic acid induces cell death in mesothelioma cells.
Biochem. Biophys. Res. Commun. 394(2):249-253 (2010).

Goto T., Sato A., Shimizu M., Adachi S., Satoh K., Iemura S., Natsume T., Shibuya H. IQGAP1 functions as a modulator of Dishevelled nuclear localization in Wnt Signaling.
PLOS ONE 8(4):e60865 (2013).

Satoh K, Yachida S, Sugimoto M, Oshima M, Nakagawa T, Akamoto S, Tabata S, Saitoh K, Kato K, Sato S, Igarashi K, Aizawa Y, Kajino-Sakamoto R, Kojima Y, Fujishita T, Enomoto A, Hirayama A, Ishikawa T, Taketo MM, Kushida Y, Haba R, Okano K, Tomita M, Suzuki Y, Fukuda S, Aoki M, Soga T.
Global metabolic reprogramming of colorectal cancer occurs at adenoma stage and is induced by MYC.
Proc. Natl. Acad. Sci. USA. 114(37):E7697-E7706 (2017).
連絡先〒997-0035山形県鶴岡市馬場町14-1
慶應義塾大学鶴岡タウンキャンパス
ksatoh [ at ] ttck.keio.ac.jp
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