Natsumi Saito
斎藤 菜摘 サイトウ ナツミ

環境情報学部講師(非常勤)
専門分野メタボロミクス、生化学
主要著作・論文・作品Publications

(1) Saito N., Ohashi Y., Soga T., Tomita M. “Unveiling cellular biochemical reactions via metabolomics-driven approaches.” Curr. Opin. Microbiol., 13 (3), 358-362, 2010.

(2) Masuda T., Saito N., Tomita M. and Ishihama Y. “Unbiased quantitation of Escherichia coli membrane proteome using phase-transfer surfactants.” Mol. Cell. Proteomics, 8, 2770-2777, 2009.

(3) Saito N., Robert M., Kochi H., Matsuo G., Kakazu Y., Soga T. and Tomita M. “Metabolite profiling reveals YihU as a novel hydroxybutyrate dehydrogenase for alternative succinic semialdehyde metabolism in Escherichia coli.” J. Biol. Chem, 284, 16442-16451, 2009.

(4) Baran R., Kochi H., Saito N., Suematsu M., Soga T., Nishioka T., Robert M., and Tomita M. “MathDAMP: a package for differential analysis of metabolite profiles.” BMC Bioinformatics, 7 (530), doi:10.1186/1471-2105-7-530, 2006.

(5)Saito N., Robert M., Kitamura S., Baran R., Soga T., Mori H., Nishioka T. and Tomita M. “A metabolomics approach for enzyme discovery.” J. Proteome Res., 5, 1979-1987, 2006.

(6)Saito N., Xu J., Hosaka T., Okamoto S., Aoki H., Bibb M. J. and Ochi K. “EshA accentuates ppGpp accumulation and is conditionally required for antibiotic production in Streptomyces coelicolor A3(2).” J. Bacteriol., 188, 4952-4961, 2006.

(7)Ohtani N., Saito N., Tomita M., Itaya M. and Itoh A. “The SCO2299 gene from Streptomyces coelicolor A3(2) encodes a bifunctional enzyme consisting of an RNase H domain and an acid phosphatase domain.” FEBS Journal, 272, 2828-2837, 2005.

(8) Jin W., Ryu Y. G., Kang S. G., Kim S. K., Saito N., Ochi K., Lee S. H. and Lee K. J. “Two relA/spoT homologous genes are involved in the morphological and physiological differentiation of Streptomyces clavuligerus.” Microbiology, 150, 1485-1493, 2004.

(9)Saito N., Matsubara K., Watanabe M., Kato F. and Ochi K. “Genetic and biochemical characterization of EshA, a protein which forms large multimers and affects developmental processes in Streptomyces griseus”: J. Biol. Chem, 278, 5902-5911, 2003.

(10) Saito N., Kurosawa K., Xu J., Okamoto S. and Ochi K. “Effect of S-adenosylmethionine on antibiotic production in Streptomyces griseus and Streptomyces griseoflavus”: Actinomycetologica, 17, 47-49, 2003.

(11)Anzai Y., Saito N., Tanaka M., Kinoshita K., Koyama Y. and Kato F. “Organization of the biosynthetic gene cluster for the polyketide macrolide mycinamicin in Micromonospora griseorubida”: FEMS Microbiol. Lett., 218 , 135-141, 2003.

(12)Xu J., Saito N., Kurosawa K., Okamoto S., Takaya N., Kobayashi M. and Ochi K. “Novel mutation in the ribosomal L11 protein gene (rplK=relC) of Streptomyces coelicolor A3(2)”: Actinomycetologica, 16, 32-36, 2002.

(13)Kawamoto S., Watanabe M., Saito N., Hesketh A., Vachalova K., Matsubara K. and Ochi K. “Molecular and functional analysis of the gene (eshA) encoding the 52-kilodalton protein of Streptomyces coelicolor A3(2) required for antibiotic production”: J. Bacteriol., 183, 6009-6016, 2001.

Patent

(1)冨田勝、曽我朋義、伊藤文、大橋菜摘 「遺伝子産物の機能同定方法及び結合物質同定方法」特許第4114075号 (April 25, 2008)/特願 2004-038647 

連絡先〒997-0035山形県鶴岡市馬場町14-1
慶應義塾大学鶴岡タウンキャンパス